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	<title>Comments on: Socked! Conclusions of The Lancet&#8217;s &#8220;end of homeopathy&#8221; study discredited</title>
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	<link>http://laughingmysocksoff.wordpress.com/2008/12/07/socked-conclusions-of-the-lancets-end-of-homeopathy-study-discredited/</link>
	<description>A weblog about science, homeopathy and spin. And socks.</description>
	<lastBuildDate>Fri, 12 Jun 2009 20:32:23 +0000</lastBuildDate>
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		<title>By: brian</title>
		<link>http://laughingmysocksoff.wordpress.com/2008/12/07/socked-conclusions-of-the-lancets-end-of-homeopathy-study-discredited/#comment-1559</link>
		<dc:creator>brian</dc:creator>
		<pubDate>Sun, 15 Feb 2009 23:38:25 +0000</pubDate>
		<guid isPermaLink="false">http://laughingmysocksoff.wordpress.com/?p=91#comment-1559</guid>
		<description>Stavros:
&#039;I explicitly said that the plural of anecdotes is not data or evidence. Medical science cannot work this way&#039;

Medical science doesnt work very well, when we see dangerous procedures, treatments like SSRI foisted on the public, only later to have labels detailing their dangers  AFTER theyve injured the public:

http://www.ssristories.com/

Why do u persist in the illusion that medical science can be trusted by the public?</description>
		<content:encoded><![CDATA[<p>Stavros:<br />
&#8216;I explicitly said that the plural of anecdotes is not data or evidence. Medical science cannot work this way&#8217;</p>
<p>Medical science doesnt work very well, when we see dangerous procedures, treatments like SSRI foisted on the public, only later to have labels detailing their dangers  AFTER theyve injured the public:</p>
<p><a href="http://www.ssristories.com/" rel="nofollow">http://www.ssristories.com/</a></p>
<p>Why do u persist in the illusion that medical science can be trusted by the public?</p>
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		<title>By: brian</title>
		<link>http://laughingmysocksoff.wordpress.com/2008/12/07/socked-conclusions-of-the-lancets-end-of-homeopathy-study-discredited/#comment-1558</link>
		<dc:creator>brian</dc:creator>
		<pubDate>Sun, 15 Feb 2009 23:03:22 +0000</pubDate>
		<guid isPermaLink="false">http://laughingmysocksoff.wordpress.com/?p=91#comment-1558</guid>
		<description>&#039;there is truly no evidence for homeopathy&#039;

thats wishful thinking. Evidence for the success of homeopathy goes back to near its inception.  A trial was conducted during  a cholera epidemic, in which patients in alondon hospital were tested with botu conventional and homeopathic medicine. The results were to be tabled in parliament. The day came when the conventional results were presented, but the homeopathic were not. But homeopathy by then had friends in high places and the results were demanded to be shown. They showed homeopathy to be successful in reducing deaths to 16% (compared top 49% in conventional medicine).
Its written up in Divided Legacy, vol 2.

Those who say there is no evidence may as well say there is no evidence for aspirin.
Jeff Garrington is just as biased as the conventional doctors in that test. His Hawks-handsaw blog is a geologist&#039;s blog, who pontificates on what he is not qualified to. he is entitled to his opinion, but thats all it is.

Disappointing of you Jeff!</description>
		<content:encoded><![CDATA[<p>&#8216;there is truly no evidence for homeopathy&#8217;</p>
<p>thats wishful thinking. Evidence for the success of homeopathy goes back to near its inception.  A trial was conducted during  a cholera epidemic, in which patients in alondon hospital were tested with botu conventional and homeopathic medicine. The results were to be tabled in parliament. The day came when the conventional results were presented, but the homeopathic were not. But homeopathy by then had friends in high places and the results were demanded to be shown. They showed homeopathy to be successful in reducing deaths to 16% (compared top 49% in conventional medicine).<br />
Its written up in Divided Legacy, vol 2.</p>
<p>Those who say there is no evidence may as well say there is no evidence for aspirin.<br />
Jeff Garrington is just as biased as the conventional doctors in that test. His Hawks-handsaw blog is a geologist&#8217;s blog, who pontificates on what he is not qualified to. he is entitled to his opinion, but thats all it is.</p>
<p>Disappointing of you Jeff!</p>
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		<title>By: fred</title>
		<link>http://laughingmysocksoff.wordpress.com/2008/12/07/socked-conclusions-of-the-lancets-end-of-homeopathy-study-discredited/#comment-1557</link>
		<dc:creator>fred</dc:creator>
		<pubDate>Wed, 04 Feb 2009 22:40:06 +0000</pubDate>
		<guid isPermaLink="false">http://laughingmysocksoff.wordpress.com/?p=91#comment-1557</guid>
		<description>you can not use a yard stick to measure a volume of water.</description>
		<content:encoded><![CDATA[<p>you can not use a yard stick to measure a volume of water.</p>
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		<title>By: paul</title>
		<link>http://laughingmysocksoff.wordpress.com/2008/12/07/socked-conclusions-of-the-lancets-end-of-homeopathy-study-discredited/#comment-1553</link>
		<dc:creator>paul</dc:creator>
		<pubDate>Sat, 13 Dec 2008 19:11:40 +0000</pubDate>
		<guid isPermaLink="false">http://laughingmysocksoff.wordpress.com/?p=91#comment-1553</guid>
		<description>Have i mentioned quantum mechanics? And i am not questioning the appropriateness of science to evaluate homeopathy. I am questioning the appropriateness of THE science used to evaluate homeopathy. I will refer here to the excellent posts that LMSO has put up here on the subject of how limited RTC&#039;s are at evaluating the processes that take place in the theraputic setting.

Oh and science, i am doing it all wrong! What is science but a way of knowing. It is knowledge gained through study or practice. There is no clear definition of how to go about &quot;science&quot;, so to say i am doing it wrong smacks of ..... well arrogance really.</description>
		<content:encoded><![CDATA[<p>Have i mentioned quantum mechanics? And i am not questioning the appropriateness of science to evaluate homeopathy. I am questioning the appropriateness of THE science used to evaluate homeopathy. I will refer here to the excellent posts that LMSO has put up here on the subject of how limited RTC&#8217;s are at evaluating the processes that take place in the theraputic setting.</p>
<p>Oh and science, i am doing it all wrong! What is science but a way of knowing. It is knowledge gained through study or practice. There is no clear definition of how to go about &#8220;science&#8221;, so to say i am doing it wrong smacks of &#8230;.. well arrogance really.</p>
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		<title>By: stavros</title>
		<link>http://laughingmysocksoff.wordpress.com/2008/12/07/socked-conclusions-of-the-lancets-end-of-homeopathy-study-discredited/#comment-1552</link>
		<dc:creator>stavros</dc:creator>
		<pubDate>Sat, 13 Dec 2008 15:10:47 +0000</pubDate>
		<guid isPermaLink="false">http://laughingmysocksoff.wordpress.com/?p=91#comment-1552</guid>
		<description>sorry paul, that&#039;s exactly what you&#039;re implying when you question the appropriateness of science to evaluate homeopathy, and when your arguments include Quantum Mechanics and appeals to not knowing everything and other ways of knowing.

Oh and, Science: you are doing it wrong paul!</description>
		<content:encoded><![CDATA[<p>sorry paul, that&#8217;s exactly what you&#8217;re implying when you question the appropriateness of science to evaluate homeopathy, and when your arguments include Quantum Mechanics and appeals to not knowing everything and other ways of knowing.</p>
<p>Oh and, Science: you are doing it wrong paul!</p>
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		<title>By: paul</title>
		<link>http://laughingmysocksoff.wordpress.com/2008/12/07/socked-conclusions-of-the-lancets-end-of-homeopathy-study-discredited/#comment-1551</link>
		<dc:creator>paul</dc:creator>
		<pubDate>Sat, 13 Dec 2008 06:13:26 +0000</pubDate>
		<guid isPermaLink="false">http://laughingmysocksoff.wordpress.com/?p=91#comment-1551</guid>
		<description>You really hven&#039;t undertood have you</description>
		<content:encoded><![CDATA[<p>You really hven&#8217;t undertood have you</p>
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		<title>By: stavros</title>
		<link>http://laughingmysocksoff.wordpress.com/2008/12/07/socked-conclusions-of-the-lancets-end-of-homeopathy-study-discredited/#comment-1550</link>
		<dc:creator>stavros</dc:creator>
		<pubDate>Sat, 13 Dec 2008 01:05:07 +0000</pubDate>
		<guid isPermaLink="false">http://laughingmysocksoff.wordpress.com/?p=91#comment-1550</guid>
		<description>&quot;&lt;b&gt;Molecular biology, and chemical mechanisms. Are these all that we know of how things interact?&lt;/b&gt;&quot; No, these are just examples.

&quot;&lt;b&gt;We have no idea how infentissimal doses interact with organisms.&lt;/b&gt;&quot; better make that &quot;no doses&quot; for dilutions more than 12C.

With your last comments both of LMSO and paul (invoking QM, human consiousness, quoting Tiller etc), it has become evident to anyone reading this thread that you are implying that science has shown homeopathy to be just a placebo, but hey, there are other ways of knowing, science is not always correct, and we have many gaps in our knowledge.

Fair enough, that&#039;s all I have been saying from the beginning: that homeopathy fails in science. In other methodologies homeopathy might prove efficacious -like what paul proposes: give treatments to patients until one of them works, and observe the changes! Way to go paul. Very scientific. No windows open for bias, human errors, and oh, our old friend, placebo effect, getting into the picture.

Science: you are doing it wrong paul!</description>
		<content:encoded><![CDATA[<p>&#8220;<b>Molecular biology, and chemical mechanisms. Are these all that we know of how things interact?</b>&#8221; No, these are just examples.</p>
<p>&#8220;<b>We have no idea how infentissimal doses interact with organisms.</b>&#8221; better make that &#8220;no doses&#8221; for dilutions more than 12C.</p>
<p>With your last comments both of LMSO and paul (invoking QM, human consiousness, quoting Tiller etc), it has become evident to anyone reading this thread that you are implying that science has shown homeopathy to be just a placebo, but hey, there are other ways of knowing, science is not always correct, and we have many gaps in our knowledge.</p>
<p>Fair enough, that&#8217;s all I have been saying from the beginning: that homeopathy fails in science. In other methodologies homeopathy might prove efficacious -like what paul proposes: give treatments to patients until one of them works, and observe the changes! Way to go paul. Very scientific. No windows open for bias, human errors, and oh, our old friend, placebo effect, getting into the picture.</p>
<p>Science: you are doing it wrong paul!</p>
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		<title>By: paul</title>
		<link>http://laughingmysocksoff.wordpress.com/2008/12/07/socked-conclusions-of-the-lancets-end-of-homeopathy-study-discredited/#comment-1549</link>
		<dc:creator>paul</dc:creator>
		<pubDate>Fri, 12 Dec 2008 20:36:39 +0000</pubDate>
		<guid isPermaLink="false">http://laughingmysocksoff.wordpress.com/?p=91#comment-1549</guid>
		<description>Paul, I am tired of you not comprehending my comments and constructing straw men arguments. I will not reply to any other comment of yours if it is full of fallacies again. I explicitly said that the plural of anecdotes is not data or evidence. Medical science cannot work this way. Also, which part of “cognitive biases” did you not understand?

i understand your arguments very well. 

But they are the same old arguments that have always been presented. And as once said by some geezer who lived around the same time as homeopathy came to be formulated. &quot;They come on in the same old way, and we shall knock them down in the same old way&quot;. Duke of Wellington.

And that way is that we shall go on treating those who come to us. We shall observe the reactions they produce and assess whether the prescription was correct or not. And how shall we know this, through observing the changes. You think that we have no concept of &quot;cognitive bias&quot;? 

If all the reactions were due to placebo why do we see restoration of health in a systematic way
return of old symptoms
from internal to external
from top to bottom 

And why when an incorrect medicine is give are these things not seen? If as you say it was all due to placebo how are these things possible? 

This is just a strawman. There are other lines of evidence as well, and homeopathy fails at every single one of them! Molecular biology? No effect. Maybe there is a chemical mechanism? No, nothing there. Nothing at all at the level of basic science. So, we can only do clinical trials. And guess what is the outcome? Failure.

Molecular biology, and chemical mechanisms. Are these all that we know of how things interact? We have no idea about the sensitivities of organisms to various stimuli? We have no idea how infentissimal doses interact with organisms. There are certainly many theories that relate to how they may act, but they are not of any importance in comparison to our goal which is to observe the restoration of health of our patients after a correct remedy is given. And it is this last point which people find the most difficult to comprehend.  

And thak you for no longer participating in this discussion. You are entitled to your opinion that my arguments are based upon a false reasoning, based upon my understanding of your understanding of how things work that is actually quite reassuring. This discussion is ultimatetly about things much weightier than our OPINIONS. I am happy with knowing that my knowledge is limited, it is because of this that i constantly check and recheck what i am doing.</description>
		<content:encoded><![CDATA[<p>Paul, I am tired of you not comprehending my comments and constructing straw men arguments. I will not reply to any other comment of yours if it is full of fallacies again. I explicitly said that the plural of anecdotes is not data or evidence. Medical science cannot work this way. Also, which part of “cognitive biases” did you not understand?</p>
<p>i understand your arguments very well. </p>
<p>But they are the same old arguments that have always been presented. And as once said by some geezer who lived around the same time as homeopathy came to be formulated. &#8220;They come on in the same old way, and we shall knock them down in the same old way&#8221;. Duke of Wellington.</p>
<p>And that way is that we shall go on treating those who come to us. We shall observe the reactions they produce and assess whether the prescription was correct or not. And how shall we know this, through observing the changes. You think that we have no concept of &#8220;cognitive bias&#8221;? </p>
<p>If all the reactions were due to placebo why do we see restoration of health in a systematic way<br />
return of old symptoms<br />
from internal to external<br />
from top to bottom </p>
<p>And why when an incorrect medicine is give are these things not seen? If as you say it was all due to placebo how are these things possible? </p>
<p>This is just a strawman. There are other lines of evidence as well, and homeopathy fails at every single one of them! Molecular biology? No effect. Maybe there is a chemical mechanism? No, nothing there. Nothing at all at the level of basic science. So, we can only do clinical trials. And guess what is the outcome? Failure.</p>
<p>Molecular biology, and chemical mechanisms. Are these all that we know of how things interact? We have no idea about the sensitivities of organisms to various stimuli? We have no idea how infentissimal doses interact with organisms. There are certainly many theories that relate to how they may act, but they are not of any importance in comparison to our goal which is to observe the restoration of health of our patients after a correct remedy is given. And it is this last point which people find the most difficult to comprehend.  </p>
<p>And thak you for no longer participating in this discussion. You are entitled to your opinion that my arguments are based upon a false reasoning, based upon my understanding of your understanding of how things work that is actually quite reassuring. This discussion is ultimatetly about things much weightier than our OPINIONS. I am happy with knowing that my knowledge is limited, it is because of this that i constantly check and recheck what i am doing.</p>
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		<title>By: jeff garrington</title>
		<link>http://laughingmysocksoff.wordpress.com/2008/12/07/socked-conclusions-of-the-lancets-end-of-homeopathy-study-discredited/#comment-1548</link>
		<dc:creator>jeff garrington</dc:creator>
		<pubDate>Fri, 12 Dec 2008 10:32:57 +0000</pubDate>
		<guid isPermaLink="false">http://laughingmysocksoff.wordpress.com/?p=91#comment-1548</guid>
		<description>Paul a homeopath would argue that the treatment is individualized. So one pill cannot treat all conditions in all the people. Hence Homeopathy cannot be tested in double blind trials. Yet the apparent positive result from going over the data from double blind trials, and suddenly these trials are ok. How come?
Basic science, 1. describe one simple lab experiment that undergraduates can perform to show the effectiveness of homeopathy, 2. how many molecules of the original substance in a shaken solution of 30x?. 
Homeopaths are currently invited to take part in a trial in order to prove the difference between each sugar pill. So far none have come forward. This offer has now been extended to University Departments offering an (extremely dubious) B.Sc in Homeopathy. If they accept the challenge and fail, would you alter your opinion about Homeopathy. If they accept and succeed I will change my opinion.
So Paul how do you know the difference. How do you know its the pill that’s made the difference, since one pill that affects one person will not affect another (individualization)  D.B.T&#039;s are used to exclude bias from any experiment, so that we are not confused by our own preconceptions. Good trials do this, poor trials allow bias. Good trials show Homeopathy no better than Placebo, do you know of any &quot;good&quot; trials that show a positive. Can you name one self limiting condition that Homeopathy can treat.
People who go to Homeopaths with self limiting conditions often do get better. The care shown, the extended consultation, are of course invaluable. &quot;Scientific Medicine&quot; can learn a lot from the patient practitioner interaction. However there is nothing in the pills, this is elaborate placebo. I suspect you make a living out of Homeopathy, so it is difficult to come to terms with this unfortunate fact, to do so and carry on would mean you are lying to your patients.
However the current blog is about a recent paper, please follow the links provided, http://hawk-handsaw.blogspot.com/2008/11/i-know-i-said-life-was-too-short.html</description>
		<content:encoded><![CDATA[<p>Paul a homeopath would argue that the treatment is individualized. So one pill cannot treat all conditions in all the people. Hence Homeopathy cannot be tested in double blind trials. Yet the apparent positive result from going over the data from double blind trials, and suddenly these trials are ok. How come?<br />
Basic science, 1. describe one simple lab experiment that undergraduates can perform to show the effectiveness of homeopathy, 2. how many molecules of the original substance in a shaken solution of 30x?.<br />
Homeopaths are currently invited to take part in a trial in order to prove the difference between each sugar pill. So far none have come forward. This offer has now been extended to University Departments offering an (extremely dubious) B.Sc in Homeopathy. If they accept the challenge and fail, would you alter your opinion about Homeopathy. If they accept and succeed I will change my opinion.<br />
So Paul how do you know the difference. How do you know its the pill that’s made the difference, since one pill that affects one person will not affect another (individualization)  D.B.T&#8217;s are used to exclude bias from any experiment, so that we are not confused by our own preconceptions. Good trials do this, poor trials allow bias. Good trials show Homeopathy no better than Placebo, do you know of any &#8220;good&#8221; trials that show a positive. Can you name one self limiting condition that Homeopathy can treat.<br />
People who go to Homeopaths with self limiting conditions often do get better. The care shown, the extended consultation, are of course invaluable. &#8220;Scientific Medicine&#8221; can learn a lot from the patient practitioner interaction. However there is nothing in the pills, this is elaborate placebo. I suspect you make a living out of Homeopathy, so it is difficult to come to terms with this unfortunate fact, to do so and carry on would mean you are lying to your patients.<br />
However the current blog is about a recent paper, please follow the links provided, <a href="http://hawk-handsaw.blogspot.com/2008/11/i-know-i-said-life-was-too-short.html" rel="nofollow">http://hawk-handsaw.blogspot.com/2008/11/i-know-i-said-life-was-too-short.html</a></p>
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		<title>By: Ulrich Berger</title>
		<link>http://laughingmysocksoff.wordpress.com/2008/12/07/socked-conclusions-of-the-lancets-end-of-homeopathy-study-discredited/#comment-1547</link>
		<dc:creator>Ulrich Berger</dc:creator>
		<pubDate>Fri, 12 Dec 2008 10:01:10 +0000</pubDate>
		<guid isPermaLink="false">http://laughingmysocksoff.wordpress.com/?p=91#comment-1547</guid>
		<description>(reposted because including a link sent me into the spam-queue... )

LMSO, before we get too deep into quantum mysticism let’s talk about simple facts. You say that “Rutten and Stolper’s comments on cut-off values for sample size are particularly telling” and cite them with

“Cut-off values for sample size were not mentioned or explained in Shang el al’s analysis. Why were eight homeopathy trials compared with six conventional trials? Was this choice predeﬁned or post-hoc? [...] We can think of no criterion that could be common to the two cut-off values. This suggests that this choice was post-hoc.”

Now, if you had read Hawk/Handsaw’s postings on this issue (linked in the very first comment by jeff garrington above) or if you had read Shang et al (2005), then you would see that this argument is bullshit. Shang et al clearly defined in their Lancet paper that

“Trials with SE [standard errors] in the lowest quartile were defined as larger trials.”

So that’s it. The interesting question is: Why was such an unfounded and ridiculous accusation published in the allegedly peer-reviewed journal called “Homeopathy”? I would like to answer by citing from Ars Technica:

“Homeopathy is not science. The journal has a negative scientific value because it does not distribute scientific knowledge, but rather disseminates wishful thinking about reality. It is the very essence of anti-science.”</description>
		<content:encoded><![CDATA[<p>(reposted because including a link sent me into the spam-queue&#8230; )</p>
<p>LMSO, before we get too deep into quantum mysticism let’s talk about simple facts. You say that “Rutten and Stolper’s comments on cut-off values for sample size are particularly telling” and cite them with</p>
<p>“Cut-off values for sample size were not mentioned or explained in Shang el al’s analysis. Why were eight homeopathy trials compared with six conventional trials? Was this choice predeﬁned or post-hoc? [...] We can think of no criterion that could be common to the two cut-off values. This suggests that this choice was post-hoc.”</p>
<p>Now, if you had read Hawk/Handsaw’s postings on this issue (linked in the very first comment by jeff garrington above) or if you had read Shang et al (2005), then you would see that this argument is bullshit. Shang et al clearly defined in their Lancet paper that</p>
<p>“Trials with SE [standard errors] in the lowest quartile were defined as larger trials.”</p>
<p>So that’s it. The interesting question is: Why was such an unfounded and ridiculous accusation published in the allegedly peer-reviewed journal called “Homeopathy”? I would like to answer by citing from Ars Technica:</p>
<p>“Homeopathy is not science. The journal has a negative scientific value because it does not distribute scientific knowledge, but rather disseminates wishful thinking about reality. It is the very essence of anti-science.”</p>
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